Our friend @CPV_Physiology raises the interesting question of transport phenomena in nature. In this third post about capillary blood flow velocity I draw to your attention a nice review of the evolution of vascular systems in animals. It is a very reasonable hypothesis that the longest-lived animals have evolved an energy-efficient cardiovascular system that delivers…… Continue reading Why capillary blood flow is Slow in longer-lived species.
To continue on from yesterday’s post, Dr Ghanem replied promptly to my request for more information on his G Tube; The G tube is a tube with narrow orifice and holes in its wall built on a scale to the capillary tube. It was designed and invented by me 39 years ago. It was later…… Continue reading more on Ghanem’s Hypothesis
For nearly a decade I have been encouraging physicians to question the century-old medical school physiology shibboleth concerning fluid volume filtration from followed by absorption to the lumen of an archetypal Capillary; the filtration – absorption model. At steady state, the extended Starling principle holds that the hydrostatic capillary pressure difference declines between arteriole and…… Continue reading Starling’s Law for the Capillary-Interstitial Fluid Transfer is Wrong?
Ernest Henry Starling CMG FRCP FRS, born 17th April 1866. Only by following out the injunction of our great predecessor William Harvey to search out and study the secrets of Nature by way of experiment, can we hope to attain to a comprehension of ‘the wisdom of the body and the understanding of the heart,’ and thereby to…… Continue reading Happy Birthday E.H. Starling
I am delighted to see a pro-con pair of manuscripts published side by side in Acta Anesthesiologica Scandinavica, and would congratulate the Journal Editors for agreeing to this style of presentation. Earlier criticisms of my work by Professor Hahn’s team did not afford me a right to reply. I also thank Imperial College London for…… Continue reading The last word… for now
Thankyou, Imperial College. From the comments I am seeing from working FFICMs on the CoViD-19 frontline, getting fluids right is one of the keys to optimising outcome. This MS is real basic science, lots of equations from Michel and Curry, but I hope my contribution to a narrative account too will ease the read. If…… Continue reading Starling Principle MS Accepted.
Are you a health care practitioner or a concerned potential patient as we approach a crisis of Intensive Care Bed supply? Would you like your voice to be heard about the Ethics of allocating scarce resources to mortally ill patients? I am a UK Intensive Care Medicine Consultant (retired from clinical practice) and I have…… Continue reading CoViD19 Family values, Doctors attitudes survey.
Universities and Colleges are now delivering Lectures to your home Computer, and FluidPhysiology.org is following suit. The first lecture commitment that I decided I had to cancel was in Leeds, Yorkshire, March 17th. I have now added a Sound file with my commentary to each Keynote slide, which plays on the Transition. I mailed a…… Continue reading Corona Virus Lockdown
Today I cast a critical eye over a recent paper from Professor Tatara’s team in Hyogo, Japan. DOI: 10.1111/aas.13548. It is a fine example of the sort of physiology experiment that can be performed in clinical practice to advance our understanding of acute body water distribution changes. The study population was 56 consecutive patients (age…… Continue reading A neat clinical experiment in fluid physiology and context sensitivity.
I redoubled efforts to have fluid physiology recognised as a subspecialty of intensive/ critical care medicine and anaesthesia/ anesthesiology with Podcasts on TopMedTalk, and was rewarded with an Endorsement from UCL’s Monty Mythen that reading the book could be “Career-changing”. Korbin Haycock, EM Physician at Loma Linda in California, called the book “Fantastic”. INTRODUCING CAREER…… Continue reading Fluid Physiology in 2020; the first month!