Why do NHS Consultants refuse to use a licensed treatment for sepsis?

Got your attention? That’s right, I am discovering that NHS Consultants are refusing to prescribe a licensed treatment for sepsis for fear of being sued or criticised by their peers.

To be exact,

“Pabrinex Intravenous High Potency, Solution for injection (‘Pabrinex’) provides additional vitamins B and C to correct deficiencies that may have occurred, for example after infections.”

Dosage for adults including the elderly:

  • For rapid therapy of severe depletion or malabsorption of water soluble vitamins B and C,particularly in alcoholism: 2 to 3 pairs of 5ml ampoules (1 pair = ampoule 1 + ampoule 2) diluted with 50ml to 100ml of infusion solution and injected over 30 minutes at intervals decided by your doctor (typically every 8 hours).

“The electronic Medicines Compendium (eMC) contains up to date, easily accessible information about medicines licensed for use in the UK. The eMC has more than 10,600 documents, all of which have been checked and approved by either the UK or European government agencies which license medicines. These agencies are the UK Medicines and Healthcare Products Regulatory Agency (MHRA) and the European Medicines Agency (EMA).”

Please, if you are one of the Sepsis Experts who are telling folk that they should not use vitamin supplements in sepsis until an adequately powered RCT confirms efficacy, at least point the coalface workers to this document and remind them that English Law requires them to disclose this information to patients or their surrogate heath choice deciders. And if you still won’t, please explain Why!


By admin

after more than a quarter of a century of intensive care medicine consultancy in one of the UK's largest teaching hospitals Dr Woodcock is on a mission to ensure the steady state Starling principle is known and understood by every student and every practitioner.

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