Can too much sodium be good for you?

Effect of isotonic versus hypotonic maintenance fluid therapy on urine output, fluid balance, and electrolyte homeostasis: a crossover study in fasting adult volunteers N. Van Regenmortel, T. De Weerdt, A. H. Van Craenenbroeck, E. Roelant, W. Verbrugghe, K. Dams, M. L. N.G. Malbrain, T. Van den Wyngaert, P. G. Jorens Br J Anaesth aex118. DOI: https://doi.org/10.1093/bja/aex118 Published:16 May 2017 From the heart of the…… Continue reading Can too much sodium be good for you?

UK now the world’s 2nd safest place for crystalloid fluid resuscitation!

Deservedly getting lots of mentions, Patterns of intravenous fluid resuscitation use in adult intensive care patients between 2007 and 2014: An international cross-sectional study Great global collaboration. The stand-out for me is that the UK participating units went from being the world’s worst offenders for colloid resuscitation (>80%) to being second only to Germany as…… Continue reading UK now the world’s 2nd safest place for crystalloid fluid resuscitation!

Ascorbic acid; what studies do we need now?

Fitz-Roy Curry at UC Davis knows more about vascular permeability than I ever will, and I am pleased to say he has offered some thoughts on Paul Marik’s claims for the Norfolk Protocol. With a little text correcting by myself; “Our lab has little experience with Vitamin C and vascular permeability regulation.  In some investigations we used…… Continue reading Ascorbic acid; what studies do we need now?