We should engineer a new crystalloid?

My post on bag wars was hardly posted when Josh Farkas’ excellent PulmCrit posted an recipe for a Universal Panacea. http://emcrit.org/pulmcrit/crystalloid/ My own foray into this arena was 19 years ago ncbi.nlm.nih.gov/pubmed/9349085 “An improved Hartmann’s solution for anaesthetists in the 1990s”. Before you read it, please note it is heavily

Faculty of 1000

Do you despair of waiting months, maybe years for Publication of research results you saw previewed at a recent Conference? Have you been frustrated by Editors who publish only positive studies in their prestigious Journal, and wondered what changes they have demanded to the submitted Manuscript? Do you wonder why

found a pearl.

I think the modern phrase is “I need to get my head around [insert here]”, and I fully accept that the glycocalyx model (Michel-Weinbaum model) is one concept it is hard to get your head around. Unfortunately you can’t be a rational prescriber of fluids if you haven’t got your

Introducing fluidphysiology.org

Re-educating the world about the steady-state Starling principle is not going to be quick or easy. Almost every textbook and Review article until very recently has been perpetuating the capillary transendothelial filtration – absorption doctrine of antiquity. In 2004 Adamson et al showed that only filtration occurs at steady state,