Albumin infusion increases the volume of distribution of albumin: a randomized clinical trial in postoperative patients after major surgery

Fresh off the press from Lund, Sweden, this interesting investigation. https://ccforum.biomedcentral.com/articles/10.1186/s13054-019-2477-7 Sixty four post-surgical patients with normal heart rate and blood pressure were given human albumin solution 5% in a volume equivalent to 25% of their normal plasma volume in case they were hypovolaemic. How did that get past the

A new Twigley – Hillman diagram

While trying to direct people away from the classic Twigley – Hillman diagram and towards my kinetic diagrams it became apparent that the standard plasma/ interstitial/ intracellular compartment boxes divided by capillary wall or cell membrane is now so ingrained that I have to take a different approach. With thanks