Midodrine again.

Why would a fluid physiologist want to point out that oral pills can be as effective as a drip and a bottle or three of human albumin solution? https://www.ncbi.nlm.nih.gov/pubmed/30312183 Albumin does seem to have a beneficial effect in certain hepatology scenarios, but researchers at the University of Cairo have found

An Update on Sodium storage

The latest contribution from Olde Engberink in Amsterdam on the emerging story of sodium storage is Open Access; https://doi.org/10.1007/s00467-019-04305-8 Olde Engberink RHG, Selvarajah V, Vogt L. Clinical impact of tissue sodium storage. Pediatr Nephrol. 2019. And a new diagram for our basic electrolyte physiology teaching for clinicians. The authors conclude

Microvascular ion transport through endothelial glycocalyx layer: new mechanism and improved Starling principle

Xi Zhuo Jiang, Yiannis Ventikos,* and Kai H. Luo*  Department of Mechanical Engineering, University College London, London, United Kingdom  Submitted 11 December 2018; accepted in final form 19 April 2019  Am J Physiol Heart Circ Physiol 317: H104–H113, 2019. First published April 26, 2019; doi:10.1152/ajpheart.00794.2018.  Well, I’ve bought a download

Well this is embarrassing…

https://www.youtube.com/watch?v=Qm86qUPS0eI The worst conference presentation I ever made has recently been posted on YouTube by someone called nsicu ru; I probably consented to recording, but did not know it had been so publicly posted. I was the second speaker in a two-presentation morning session, and the first speaker who disapproves

Now on YouTube

FluidPhysiology announces it’s premiere on YouTube, launched yesterday to our twitter followers. The link is; youtu.be/8-w_MO38Umo If you search The Starling Principle or Starling equation or capillary fluid exchange you’ll find many enthusiastic video bloggers, from medical students to professors, explaining the traditional filtration/ reabsorption concept. Some of them have

Albumin infusion increases the volume of distribution of albumin: a randomized clinical trial in postoperative patients after major surgery

Fresh off the press from Lund, Sweden, this interesting investigation. https://ccforum.biomedcentral.com/articles/10.1186/s13054-019-2477-7 Sixty four post-surgical patients with normal heart rate and blood pressure were given human albumin solution 5% in a volume equivalent to 25% of their normal plasma volume in case they were hypovolaemic. How did that get past the