Glycocalyx Special Edition

The American Journal of Pathology Special edition opens with an overview of nanomechanics; the connections between the luminal surface endothelial glycocalyx and the intra-endothelial cortex, largely composed of actin molecules, is emphasised. The sequelae of endothelial glycocalyx injury include enhanced vascular permeability, tissue oedema, augmented leukocyte adhesion, platelet aggregation, and

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Can we measure the endothelial glycocalyx?

This month we read an interesting experiment by Sweden’s Robert Hahn, an attempt to quantify the intravascular volume that is not the free-flowing plasma we sample by venesection or by drawing from an intravascular catheter. https://icm-experimental.springeropen.com/articles/10.1186/s40635-020-00317-z We have to thank Fitz-Roy Curry in California for much of our current knowledge about

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The last word… for now

I am delighted to see a pro-con pair of manuscripts published side by side in Acta Anesthesiologica Scandinavica, and would congratulate the Journal Editors for agreeing to this style of presentation. Earlier criticisms of my work by Professor Hahn’s team did not afford me a right to reply. I also

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