The latest contribution from Olde Engberink in Amsterdam on the emerging story of sodium storage is Open Access; https://doi.org/10.1007/s00467-019-04305-8 Olde Engberink RHG, Selvarajah V, Vogt L. Clinical impact of tissue sodium storage. Pediatr Nephrol. 2019. And a new diagram for our basic electrolyte physiology teaching for clinicians. The authors conclude
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after more than a quarter of a century of intensive care medicine consultancy in one of the UK's largest teaching hospitals Dr Woodcock is on a mission to ensure the steady state Starling principle is known and understood by every student and every practitioner.
Endothelial cells; there are sex differences.
I guess we’d not argue that there are likely to be differences in the microvascular physiology of men and women. Professor Virginia Huxley is the Director of the United States National Center for Gender Physiology and Professor in the Department of Medical Pharmacology and Physiology, Missouri. In a recent paper
Microvascular ion transport through endothelial glycocalyx layer: new mechanism and improved Starling principle
Xi Zhuo Jiang, Yiannis Ventikos,* and Kai H. Luo* Department of Mechanical Engineering, University College London, London, United Kingdom Submitted 11 December 2018; accepted in final form 19 April 2019 Am J Physiol Heart Circ Physiol 317: H104–H113, 2019. First published April 26, 2019; doi:10.1152/ajpheart.00794.2018. Well, I’ve bought a download
Well this is embarrassing…
https://www.youtube.com/watch?v=Qm86qUPS0eI The worst conference presentation I ever made has recently been posted on YouTube by someone called nsicu ru; I probably consented to recording, but did not know it had been so publicly posted. I was the second speaker in a two-presentation morning session, and the first speaker who disapproves
Now on YouTube
FluidPhysiology announces it’s premiere on YouTube, launched yesterday to our twitter followers. The link is; youtu.be/8-w_MO38Umo If you search The Starling Principle or Starling equation or capillary fluid exchange you’ll find many enthusiastic video bloggers, from medical students to professors, explaining the traditional filtration/ reabsorption concept. Some of them have
Infamy, infamy, why have they got it in for me?
Debates in fluid therapy recommendations can get a bit hot; first it was Colloids versus Crystalloids, then it was Chloride Max versus Chloride Lite solutions. Now I enjoy a good civilised debate, even a Fluid Controversy if that’s what it takes to attract the attention of ticket-buying Conference Delegates, but
Oedema as a drug side effect
With thanks to ace Tweep @tony_breu, this is an important topic to be considered in the light of steady-state Starling physiology. Indeed I am not aware of any up-to-date review in the literature, so if one or two of you want to use this as a basis for such a
Albumin infusion increases the volume of distribution of albumin: a randomized clinical trial in postoperative patients after major surgery
Fresh off the press from Lund, Sweden, this interesting investigation. https://ccforum.biomedcentral.com/articles/10.1186/s13054-019-2477-7 Sixty four post-surgical patients with normal heart rate and blood pressure were given human albumin solution 5% in a volume equivalent to 25% of their normal plasma volume in case they were hypovolaemic. How did that get past the
A new Twigley – Hillman diagram
While trying to direct people away from the classic Twigley – Hillman diagram and towards my kinetic diagrams it became apparent that the standard plasma/ interstitial/ intracellular compartment boxes divided by capillary wall or cell membrane is now so ingrained that I have to take a different approach. With thanks
New in 2019
The Manuscript for my Textbook is now with the Publisher, who seems keen to get it on your bookshelf as soon as possible. I shall now try to return to maintaining this website for Starling Ambassadors.