Magic Eye view of glycocalyx

Seeing is believing, even if what you want to see is actually unseeable.  My last post has reminded me of Kenton Arkill’s wonderful 3-D reconstruction of a rat peritubular capillary’s glycocalyx. Take a stereoscopic look; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808814/figure/F5/ Sad to say, I can’t see it; my eyes adapt near rather than far,

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An optimistic view of OPTIMISE II?

Rupert Pearse’ OPTIMISE trial published in 2014 found that “use of a cardiac output–guided hemodynamic therapy algorithm compared with usual care did not reduce a composite outcome of complications and 30-day mortality.” My concern about the protocol was that it obliged research anaesthetists to give colloid solutions to all the

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Albumin, the EGL, vascular permeability and trout fishing.

Jon-Emile Kenny is a New York physician who has recently joined the FOAMEd movement, and is opening his PulmCrit account with a blast around the steady-state Starling principle. http://pulmccm.org/main/2016/ards-review/revised-starling-principle-implications-rational-fluid-therapy/ It seems JE has read RSE&GM 2012 and is concerned about his propensity to prescribe hyperoncotic albumin with furosemide to cirrhotic

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